Prices

Zepbound price: list, self-pay tiers, savings card and Medicare, dated

Zepbound (tirzepatide) costs as of September 2026: the $1,088 list, LillyDirect self-pay tiers, the 45-day refill rule, the $25 card, and Medicare.

3 min readUpdated September 4, 2026By FormBlends editorial team7 sourcesEducational, not medical advice

Zepbound: list price versus manufacturer self-pay tiers

From the data
Zepbound prices per fill: list $1,088, self-pay from $299 at 2.5 mg.Horizontal bars. List price: $1,088; 2.5 mg self-pay: $299; 5 mg self-pay: $399; 7.5 mg self-pay: $499 ($449 with the refill condition); 10 mg self-pay: $699 ($449 with the refill condition); 12.5 mg self-pay: $699 ($449 with the refill condition); 15 mg self-pay: $699 ($449 with the refill condition).$0$500$1,000List price$1,0882.5 mg self-pay$2995 mg self-pay$3997.5 mg self-pay$499 ($449)10 mg self-pay$699 ($449)12.5 mg self-pay$699 ($449)15 mg self-pay$699 ($449)Vertical mark and bracketed figure: price under the manufacturer's refill-window condition
US dollars for one standard fill (4 doses, 28 days). LillyDirect self-pay (single-dose vials or single-patient-use KwikPen) Lilly states the regular one-month price as $299 (2.5 mg), $399 (5 mg), $499 (7.5 mg) and $699 (10, 12.5 and 15 mg) for the KwikPen or four single-dose vials, with 7.5 mg and above at $449 under the 45-day refill condition. Read on 2026-09-04. Source: Lilly: Zepbound savings and self-pay pricing.

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Dated brand and program prices with sources: price index. For the network cost report see the FormBlends GLP-1 cost report.

Zepbound is tirzepatide approved for chronic weight management and for obstructive sleep apnea with obesity. It has one list price, a self-pay ladder that steps with the strength, a commercial savings card with two caps, and, since July 2026, a flat Medicare price for one of its three presentations. Each is below with the page it came from.

List price

$1,088 per month, as quoted in the February 6, 2026 White House release announcing TrumpRx.gov. Lilly's own pricing page for Zepbound renders its figure in the browser and could not be captured as text on September 4, 2026; the government release is the most recent dated public statement of the monthly list figure. See the list-price table for every product.

Self-pay through LillyDirect

Lilly's savings page, read September 4, 2026, states one-month self-pay prices for the single-patient-use KwikPen or four single-dose vials:

StrengthRegular pricePrice within the 45-day refill window
2.5 mg$299$299
5 mg$399$399
7.5 mg$499$449
10 mg$699$449
12.5 mg$699$449
15 mg$699$449

The $449 figure is a purchase offer, Lilly's Self Pay Journey Program, and it holds only if the refill is bought within 45 days of the previous fill's delivery. Miss the window and the regular column applies until you re-qualify. The HCP page dates the current program from February 23, 2026.

For context on how fast this ladder has moved: Lilly's February 25, 2025 release priced the vials at $349 (2.5 mg), $499 (5 mg) and $499 for 7.5 and 10 mg within the refill window, with $599 and $699 regular. The November 6, 2025 agreement with the U.S. government brought the multi-dose pen to $299 at the lowest strength and up to $449 at higher ones, and the vial followed on December 1, 2025. Details and the program mechanics are on the LillyDirect page.

Savings card with commercial insurance

If a commercial plan covers Zepbound, the Lilly card lets you pay as little as $25 for a 1-, 2- or 3-month fill. The card pays at most $100 per one-month fill ($200 per two-month, $300 per three-month) and at most $1,300 per calendar year, and it expires December 31, 2026. Medicare, Medicaid and other government beneficiaries are excluded. If your copay is $150, the card takes it to $50, not $25; if your plan does not cover Zepbound at all, the card does nothing and the self-pay ladder is the fallback. The savings-card page works through the caps for every product.

Medicare

Zepbound is in the Medicare GLP-1 Bridge: eligible Part D enrollees pay $50 per month from July 1, 2026 to December 31, 2027. Two constraints matter. CMS covers only the Zepbound KwikPen; the single-dose vial and single-dose pen are excluded, and pen needles are not included. And the Bridge is for weight management under CMS clinical criteria (BMI 35 or more; BMI 30 or more with heart failure, uncontrolled hypertension or chronic kidney disease; BMI 27 or more with pre-diabetes, prior heart attack, prior stroke or symptomatic peripheral artery disease), not for a sleep apnea prescription, which goes through regular Part D. The Medicare page has the full picture, including why Part D could not cover it for weight loss before.

What a month really costs

A 28-day fill is 13.04 fills a year. At $449 that is $5,853 a year, or $488 per calendar month, not $449. Run your own strength and program through the calculator above; it shows the arithmetic and lets you add a telehealth membership or pen needles on top.

Compounded tirzepatide is a different product

Compounded tirzepatide vials are priced by the pharmacy or telehealth provider, not by a list price, and they are not FDA approved or interchangeable with Zepbound. The compounded price ranges page records what providers publish, with a methodology, and the comparison page explains why a per-milligram figure across the two is arithmetic rather than a like-for-like comparison. FormBlends, which runs this site, sells compounded tirzepatide; its offer appears in that table under the same rules as every other provider.

Questions people ask

Is the Zepbound vial cheaper than the KwikPen?

No. Lilly's savings page states the same one-month price for the single-patient-use KwikPen or four single-dose vials at each strength: $299 for 2.5 mg, $399 for 5 mg, and $449 for 7.5 mg and above under the 45-day refill condition (read September 4, 2026). The difference is that the Medicare GLP-1 Bridge covers only the KwikPen.

What happens to the $449 price if I refill late?

The $449 price for 7.5 mg and above is a purchase offer that requires the refill to be bought within 45 days of the previous delivery. Outside that window Lilly's stated regular price applies: $499 for 7.5 mg and $699 for 10, 12.5 and 15 mg.

Sources (7)

  1. Lilly: Zepbound savings and self-pay pricing (KwikPen and vial tiers, 45-day condition, savings card terms) Accessed September 4, 2026.
  2. Lilly: Zepbound coverage, affordability and savings (HCP page: vial and KwikPen self-pay tiers, Self Pay Journey Program from February 23, 2026) Accessed September 4, 2026.
  3. Lilly: Zepbound Medicare Part D page (Bridge covers KwikPen only) Accessed September 4, 2026.
  4. White House release, February 6, 2026: launch of TrumpRx.gov (Zepbound original price $1,088 per month) Accessed September 4, 2026.
  5. Lilly press release, February 25, 2025: additional Zepbound vial doses (prior $349 to $699 tiers) Accessed September 4, 2026.
  6. Lilly press release, November 6, 2025: agreement with the U.S. government ($299 to $449 multi-dose pen, Medicare $50) Accessed September 4, 2026.
  7. CMS: Medicare GLP-1 Bridge, information for providers Accessed September 4, 2026.

Canonical URL: https://formblendspricing.com/prices/zepbound. Written by the FormBlends editorial team. This page is educational and is not medical advice; see the medical disclaimer.